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Global Health Resources

​​​APHL publishes laboratory practice guides, training manuals and materials to support development of laboratory plans, policies and infrastructure.

Questions?

Contact the Global Health team: [email protected]

About Our Work

Technical Resources

Laboratory Data Systems

Fact Sheet
2025

Overview of the Open Laboratory Data Repository platform, for ministries and country-level public health systems

Global Health, Informatics, Data Management
Fact Sheet
2025

Overview of the Open Laboratory Data Repository platform's functional components, for software developers, engineers and IT administrators

Global Health, Informatics, Data Management
Guide / Guidance
2019

This guide follows the sequence of an international LIS implementation. Users can begin with the section that corresponds to their place in the LIS implementation cycle.

Global Health
Guide / Guidance
2019

A tool to provide laboratories with questions to discuss when evaluating data quality and data use of the laboratory information system (LIS).

Global Health
Guide / Guidance
2019

A means for laboratories to verify that training and LIS implementation have been appropriately completed.

Global Health
Guide / Guidance
2019

A tool to assign roles and responsibilities for completing tasks related to the laboratory information system (LIS).

Global Health
Guide / Guidance
2019

A framework for a laboratory to craft their own steps and activities that need to be carried out for the laboratory information system (LIS)​ to succeed.

Global Health
Fact Sheet
2024

This guide explores the utility and opportunities available with integrated laboratory information systems (LIS), for both individual laboratories and national-level public health systems.

Global Health, Informatics
Fact Sheet
2025

High level summary of global public health data exchange solutions.

Global Health, Informatics
Guide / Guidance
2025

A guide for laboratories around the world to design a road map for establishing a data exchange platform that meets your circumstances and needs.

Global Health, Informatics
Guide / Guidance
2025

Una guía que los laboratorios de todo el mundo diseñen un proceso para establecer una plataforma de intercambio de datos que se ajuste a sus circunstancias y necesidades

Global Health, Informatics
Guide / Guidance
2019

A framework of tiered positions and roles that work with and support the laboratory information system (LIS).

Global Health
Guide / Guidance
2019

A tool to monitor and assess the day-to-day functioning of the laboratory information system (LIS).

Global Health
Tool / Work Aid
2018

This document provides guidelines to laboratory managers on how to craft and implement a detailed data backup and recovery plan and carry out regular backups of data and applications.

Global Health
Guide / Guidance
2019

A tool to evaluate data quality and turn around time within the laboratory information system (LIS).​

Global Health
Guide / Guidance
2019

A set of questions to evaluate steps taken to ensure ownership of the laboratory information system (LIS) and assess laboratory and national policies to support effective utilization of the LIS.

Global Health
Report
2020

Select findings from the 2019 APHL All-Hazards Laboratory Preparedness Survey highlight the importance of public-private partnerships in responding to public health threats.

Public Health Preparedness and Response
Fact Sheet
2024

Learn more about how we're improving antimicrobial resistance data collection and reporting in Zambia.

Global Health, Informatics, Antimicrobial Resistance, Laboratory Operations and Systems, Data Management
Fact Sheet
2024

Learn how we're improving influenza data integration practices in Kenya to enhance surveillance efforts.

Global Health, Informatics, Respiratory Diseases, Data Management
Guide / Guidance
2024

Learn how to protect laboratory data and ensure data confidentiality, integrity and availability around the world.

Global Health, Informatics, Data Management

Sequencing and Bioinformatics

OXFORD NANOPORE TECHNOLOGIES: MIDNIGHT PROTOCOL

THERMOFISHER PLATFORMS: AMPLISEQ PROTOCOL

Illumina

COVIDSeq Protocols

ARTIC Protocols

MiSeq Sequencer Documents

COVIDSeq Protocols

ARTIC Protocols

Sequencer Documents

COVIDSeq Protocols

Food Safety - PulseNet International

Training Series

Journal Articles

Standard Operating Procedures

APHL, in collaboration with CDC, is committed to assisting all PulseNet participating laboratories (USA and International) in achieving the highest quality of data before sharing sequencing results with their respective countries and/or regions. Part of that commitment consists of the development and implementation of standardized laboratory and analysis protocols that enable the exchange and comparison of whole genome sequence data between laboratories.

The PulseNet Standard Operating Procedures (SOPs) provided below were established specifically for the PulseNet USA laboratories, with the understanding that most of the PulseNet USA standards will apply, within varying degrees, to our PulseNet International partners. We encourage PulseNet International laboratories to adopt these standards whenever possible and to modify them in a manner consistent with their internal policies or guidelines established by their institution, state, or country.

For questions concerning PulseNet International SOPs, please contact [email protected]. 

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Training and Professional Development

For a complete list of our offerings, visit:

Global Health Training and Professional Development