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Author: josh.rowland

6PPD-Quinone and Tire Treadwear Chemicals:
Preparing Laboratories for When the Rubber Meets the Road
Part 1 | Emerging Contaminants in Tire Treadwear: Exposure Pathways, Health Effects, and the 6PPD-Quinone Discovery
January 26, 2026 | 2:00 – 3:00 pm ET Course # 000-602-26
Part 2 | Detecting 6PPD-Quinone: Sampling Challenges and Analytical Approaches
January 28, 2026 | 2:00 – 3:00 pm ET Course # 000-603-26

DESCRIPTION
6PPD-quinone (6PPDQ), a chemical transformation product released from tire treadwear particles (TTPs), is emerging as a toxic contaminant in US waterways, causing acute harm to aquatic species and concern for potential human health effects. A 2020 study investigating unexplained coho salmon mortality in the Pacific Northwest implicated 6PPDQ, which has since been found in stormwater, surface water and sediment across multiple states. As attention grows around TTPs and related contaminants released from tires used in transportation, construction, playgrounds, and sports surfaces, laboratories need to be prepared to determine whether to implement testing in their jurisdiction and to understand the key sampling and analytical considerations involved.
Join this webinar series to learn about current TTP and 6PPDQ research on environmental occurrence, human and ecological health effects, biomonitoring exposure markers, sampling approaches and laboratory methods to help address these contaminants of emerging concern.
AUDIENCE
This webinar in intended for state, territorial and local public health and environmental laboratories and their partners, and anyone else interested in learning more about TTPs and 6PPDQ.
OBJECTIVES
After completing this webinar series the participant will be able to:
Describe the sources, environmental occurrence, and ecological and health impacts of TTPs and 6PPDQ.
Outline sampling approaches, laboratory methods, and quality considerations for detecting 6PPDQ and relevant TTP markers in environmental samples.
Series moderator
Sin Urban, PhD, division chief, Division of Environmental Sciences, Laboratories Administration, Maryland Department of Health
Accessibility
In compliance with the Americans with Disabilities Act, individuals seeking special accommodations must email a request to Emily Potter (emily.potter@aphl.org) prior to the live webinar. Closed captions will be available with the webinar recording.
Learn More
For more information about this webinar, please email webinars@aphl.org.
Part 1 | Emerging Contaminants in Tire Treadwear: Exposure Pathways, Health Effects, and the 6PPD-Quinone Discovery
January 26, 2026 | 2:00 – 3:00 pm ET Course # 000-602-26
DESCRIPTION
This session summarizes emerging research on tire-associated contaminants, focusing on 6PPD-quinone (6PPDQ) and associated health effects across environmental and human exposure contexts. Speakers from the Environmental Protection Agency and the Washington State Department of Health will review biomonitoring and method development efforts and discuss how risk assessment, fate and transport contributed to its identification.
OBJECTIVES
After completing this webinar the participant will be able to:
Characterize the current landscape of TTPs, including 6PPDQ, with respect to human health relevance, emerging biomonitoring data, and ongoing method development.
Explain how prospective risk assessment, fate and transport, and aquatic toxicity contributed to the discovery and prioritization of 6PPDQ.
Speakers
Mark Jankowski, MSPH, PhD, senior toxicologist, Region 10, Laboratory Services and Applied Science Division, US EPA
Mallory Little, MPH, toxicologist, Office of Environmental Public Health Sciences, Washington State Department of Health
Part 2 | Detecting 6PPD-Quinone: Sampling Challenges and Analytical Approaches
January 28, 2026 | 2:00 – 3:00 pm ET Course # 000-603-26
DESCRIPTION
This session presents strategies for detecting 6PPDQ in environmental samples. Speakers from EPA and Vancouver Island University will highlight sampling and analytical approaches, including USEPA Draft Method 1634 and mass spectrometry options, and demonstrate how trend analysis can inform laboratory planning and interpretation.
OBJECTIVES
After completing this webinar the participant will be able to:
Identify key considerations for sampling 6PPDQ, including when, where and how to sample, and strategies to address high spatial and temporal variability.
Evaluate established and emerging analytical approaches, including USEPA Draft Method 1634, for measuring 6PPDQ, considering mass spectrometry techniques, performance metrics, cost and scalability.
Speakers
Erik Krogh, PhD, P.Chem., co-director, Centre for Health and Environmental Mass Spectrometry, Department of Chemistry, Vancouver Island University
Barry V. Pepich, PhD, laboratory director, Region 10, Laboratory Services and Applied Science Division, US EPA

enroll for Free
Enrollment for Part 1 and Part 2 is required to access the live webinars. If you need assistance with enrollment, send us an email. To participate in this live webinar, log in to the APHL Learning Center (ALC) and follow these instructions. If accessing the APHL Learning Center (ALC) for the first time, create a free APHL account.
Level of Instruction:
BASIC: Entry level; no prior knowledge of the subject is necessary.

By registering for this event, you are consenting to have your information shared with APHL event collaborators, such as the Centers for Disease Control and Prevention and Public Health Laboratories. We will not, in any circumstances, share your information with other individuals or organizations without your permission, including corporations or individuals, except when applicable by law. We do not sell, communicate or divulge your information to any mailing lists.
This webinar is supported by Cooperative Agreement number NU600E000104 funded by the Centers for Disease Control and Prevention. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention or the Department of Health and Human Services, or APHL and member laboratories. This project was 100% funded with federal funds from a federal program of $1,379,661.

6PPD-Quinone and Tire Treadwear Chemicals:
Preparing Laboratories for When the Rubber Meets the Road
Part 1 | Emerging Contaminants in Tire Treadwear: Exposure Pathways, Health Effects, and the 6PPD-Quinone Discovery
January 26, 2026 | 2:00 – 3:00 pm ET Course # 000-602-26
Part 2 | Detecting 6PPD-Quinone: Sampling Challenges and Analytical Approaches
January 28, 2026 | 2:00 – 3:00 pm ET Course # 000-603-26

Training Event Instructional Video
Please view this before getting started.

This is an invitation-only event. Please contact emily.potter@aphl.org for more information.

The Association of Public Health Laboratories (APHL) sponsors educational programs on critical issues in laboratory science.

For a complete list of APHL webinars, trainings and events visit: www.aphl.org/LabTraining